Brain Match

Brain imaging is a powerful technology used to study brain disorders like Alzheimer’s Disease and Schizophrenia. To detect subtle differences between brains, sometimes thousands of brain scans need to be compared.

A critical step in this kind of study is to align images of the different brains so the anatomy matches. This process is called registration, and is a complex task, prone to errors. While a researcher will typically visually check that the brains match after registration, there are no established guidelines to judge of the quality of a registration.

This project builds on simple guidelines to assess the quality of brain registration (how well the brain images match). We hope to find that these guidelines produce consistent ratings across users. If we generate enough data we may even be able to “train computers” to better judge quality of brain registration, which would help us process huge amounts of data!

We need your help to improve brain registration!